Hypertension is an extremely common disease that affects approximately 30% of adults in the United States, while approximately 25% of people in Korea are affected by hypertension. Hypertension is a major factor in the morbidity and mortality of cardiovascular disease. Periodontitis, a chronic inflammatory disease of the periodontal tissue, affects about 50% of the total population. In the last decade, periodontitis has received great social attention because of its association with many diseases (e.g. diabetes, metabolic syndrome and some macrovascular complications such as stroke and coronary heart disease). It is well known that inflammatory and immune responses in periodontitis can induce the production of inflammatory cytokines and lead to the destruction of epithelial cells and connective tissue. Periodontitis may lead to the development of systemic inflammation and therefore may promote the development of atherosclerosis as well as dyslipidemia, which can cause systemic diseases such as atherosclerosis and cardiovascular disease. Recently, several studies have shown that periodontitis is involved in the development and progression of hypertension. However, there is limited research on whether oral health education campaigns have an impact on the prevention and control of hypertension. In this study, data from the National Nutrition and Health Survey (NNHS) were used to assess the relationship between oral hygiene behaviors and hypertension in the overall Korean population. The National Nutrition and Health Survey included 19,560 adults and resulted in a complete data set. By applying data from this survey, the relationship between the prevalence and control of hypertension and numerous variables, including oral hygiene behaviors, was analyzed. The results found that after adjusting for various factors including periodontitis, the prevalence of hypertension decreased with more frequent tooth brushing. The same relationship was found for individuals without periodontitis in the subgroup analysis. In particular, the level of systolic blood pressure decreased progressively with increasing frequency of brushing and the number of secondary oral products. The prevalence of hypertension was 1.195 (1.033-1.383) in individuals who rarely brushed their teeth or brushed only once a day, compared to those who brushed immediately after meals. In conclusion, individuals with poor oral hygiene behaviors are more likely to develop hypertension, and this relationship can occur even before individuals develop periodontitis. Oral hygiene behavior can be considered an independent risk factor for hypertension, and good oral hygiene can contribute to the prevention and control of hypertension.