The inability to have an erection after two days of uninterrupted erection may be caused by abnormal penile erection, erectile dysfunction, psychological stress, etc., and can be treated by general treatment, medication, and psychological treatment according to their own situation. 1. Abnormal penile erection: after the patient is subjected to external stimulation, it may lead to abnormal penile erection, causing the symptom of inability to have erection after two days of uninterrupted erection, which can be treated conservatively, such as the application of epinephrine, etc., as well as surgical treatments, such as penile cavernous penile body-head bypass surgery. 2. Erectile dysfunction: after suffering from erectile dysfunction, the cavernous blood flow perfusion is abnormal, and the patient will also have the symptom of not being able to have an erection after two days of uninterrupted erection. Patients can take sildenafil, testosterone undecanoate gel pills and other medications to improve the symptoms of not being able to have an erection. 3. Psychological stress: the inability to have an erection after two days of uninterrupted erection may also be related to psychological stress. Patients should receive timely psychological treatment to reduce behavioral anxiety and increase sexual health knowledge. All the above drugs need to pay attention to the side effects and adverse reactions of drugs, please use the above drugs under the guidance of a doctor. After two days of uninterrupted erection can not erect patients should go to the hospital in time to receive regular treatment to avoid aggravation of the condition.