Simple low uric acid usually has no obvious symptoms and manifestations, but low uric acid caused by acute hepatic necrosis, abnormal secretion of antidiuretic hormone, renal tubular pathology and other diseases may be accompanied by anorexia, drowsiness, lymph node enlargement and other symptoms, it is recommended that the patient go to the hospital as soon as possible, to clarify the cause of the disease, and to the cause of the treatment. 1. Acute hepatic necrosis: purines can produce uric acid after metabolized by liver, when uric acid is lowered in acute hepatic necrosis, patients will also have anorexia, bloating, nausea, jaundice and other symptoms. 2. Abnormal secretion of antidiuretic hormone: Abnormal secretion of antidiuretic hormone will lead to the increase of water in the body, the value of uric acid is low, and the patient will also have symptoms such as drowsiness, weakness and agitation. 3. renal tubular lesions: renal tubular lesions can lead to increased uric acid discharge, patients will appear uric acid drop, polyuria, dizziness, nausea and other symptoms. Patients with too low uric acid are advised to consult the doctor in time for early diagnosis and treatment to prevent delaying the condition.