Lower extremity angiography is a common and widely used adjunctive test in clinical practice, mainly to detect the presence of thrombosis in the lower extremity blood vessels, the presence of valvular insufficiency in the traffic branches of the deep and superficial veins, and the detection of arteriovenous inflammation. The main operation is to push the contrast medium from the superficial vein of the dorsum of the foot while the patient’s lower extremity is in a relaxed state, and a tourniquet is tied around the ankle to block the anterior venous return during the imaging, forcing the contrast medium into the deep venous system. Adequate visualization of the deep veins can be achieved while reducing and blocking the filling of the superficial veins. With imaging acquisition including x-ray as well as CT full scan situations, the entire lower extremity vessels can be followed and localized throughout to detect specific vascular lesions. It is important to note that the patient must cooperate with the physician in rotating the body position, inhaling, and holding the breath to follow the instructions in order to acquire a more realistic and meaningful lower extremity angiographic image.