Spot generally refers to freckles and chloasma, and melanosis is mostly caused by inflammation stimulation. Spot removal and melanosis can be removed by choosing medication, laser and other methods according to different causes. 1. Freckle: Freckle is a kind of brown spot pigmentation spot commonly found on the face. Commonly used treatments include Q-switched ruby laser with wavelength of 694nm, emerald green gemstone laser with wavelength of 755nm, or IPL treatment, which has better efficacy, and attention should be paid to avoiding light after the operation. 2. Melasma: Melasma is a symmetrical yellowish-brown pigmentation spot on the face, which is common among young and middle-aged women. It can be treated with external decolorizing agent such as 2%~5% hydroquinone cream, or oral vitamin C, vitamin E and tranexamic acid. Can also IPL treatment Q switch large spot low energy laser treatment effect. 3. Melanosis: can be used externally decolorizing agents such as 2% ~ 5% hydroquinone cream, or azelaic acid cream in the pigmentation, if necessary, feasible laser treatment. To get rid of spots and melanin pigmentation, you should consult a doctor in time, under the guidance of a professional doctor to choose the appropriate treatment according to the different spots, and avoid self-medication.