Eating anti-inflammatory drugs stomach upset is mostly due to drug-induced gastrointestinal mucosal damage, mostly seen in gastric mucosal congestion, edema, erosion, gastric acid secretion, often given acid inhibitors and drugs to protect the gastric mucosa. Acid-suppressing drugs can choose H2 receptor antagonists or proton pump inhibitors, as follows: 1, proton pump inhibitors: including omeprazole, lansoprazole, rabeprazole, pantoprazole, esomeprazole. 2, gastric mucosal protection agents: commonly used aluminum sulfate, magnesium aluminum carbonate, bismuth pectin, etc.. At the same time, patients are given light, warm and soft, easy to digest food. If the symptoms are not relieved or aggravated after 3-5 days of oral intake, they should immediately go to the hospital for a systematic examination including gastroscopy, to further clarify the location, degree and specific cause of the gastrointestinal tract injury, and individualized treatment should be given.