Lymph node refers to the obvious enlargement of lymph nodes compared with normal, and there are many causative factors, which are commonly as follows: First, caused by bacterial or viral infection, lymph nodes are part of the body’s immune organs, when the body suffers from exogenous invasion, such as bacterial or viral infections, which can lead to an increase in the number of lymphocytes, and this will cause lymph nodes to increase in size, and can be initially determined by checking the routine blood and ultrasound, and then later on Regular anti-inflammatory treatment and anti-viral treatment can be carried out to relieve the swelling and pain of lymph nodes. Secondly, lymph node metastasis of malignant tumors, which is often caused by metastasis through lymphatic channels, need to carry out lymph node puncture biopsy, resection of lymph node biopsy to clarify the nature of the need for active resection of the primary lesion, and then give chemotherapy, radiotherapy, immunotherapy for radical treatment. Thirdly, autoimmune diseases can also lead to enlarged lymph nodes. In conclusion, if there are obvious lymph node abnormalities, it is necessary to go to the hospital in time for diagnosis and treatment.