The need for treatment of high bile acids is determined by the cause of the disease. Physiologic hyperglycocholic acid does not require specific treatment, while pathologic hyperglycocholic acid needs to be treated according to the cause.
Glycyrrhetinic acid is a kind of bile acid which mainly exists in hepatocytes, and is generated by the combination of primary bile acid and glycine after a series of enzymatic reactions of cholesterol, including goose deoxycholic acid and bile acid. The level of glycolic acid in normal human serum is 0.4-2.98mg/L, which can be used to determine whether liver function is normal.
Elevated glycolic acid can be seen in certain physiologic conditions, such as transient elevations following a high-fat diet and physiologic elevations (not more than 10 mg/L) during pregnancy. Physiological elevation of glycolic acid does not require special treatment and can return to normal on its own.
On the other hand, high glycolic acid caused by hepatocellular carcinoma, viral hepatitis, biliary obstruction, bile duct stones and other pathologic factors requires etiologic treatment. For example, patients with hepatocellular carcinoma need to choose surgical treatment, radiotherapy and chemotherapy according to the stage of tumor; patients with viral hepatitis can be treated with interferon and other antiviral drugs; and patients with biliary tract obstruction can be treated with surgical operation to relieve the obstruction, etc. It is recommended that patients with high bile acids should be treated with special treatment.
It is recommended that people with high glycolic acid should standardize the treatment and medication under the guidance of doctors after eliminating physiological factors.