The main symptoms of upright hypotension and dying sensation are different. Upright hypotension is characterized by dizziness and fatigue while dying sensation is characterized by severe chest pain and fear. Upright hypotension refers to a drop in blood pressure that occurs within 3 minutes of changing from lying down to standing up, with patients experiencing dizziness, weakness, fatigue, nausea, and headache, which can occur in dehydrated, frail elderly, and blood loss patients. The sense of near death is characterized by severe chest pain, panic, choking, and the feeling of being near death, which can be seen in patients with acute myocardial infarction, aortic coarctation, and panic attacks. Upright hypotension and near-death sensation are easy to distinguish according to the symptoms. If patients have upright hypotension or near-death sensation, they need to go to the hospital in time, and get prompt treatment after clarifying the cause of the disease.