Isolated plasmacytoma is a relatively rare malignant plasma cell disease, manifested by localized swelling, pain and other symptoms, and can be treated with radiotherapy and surgery.
Isolated plasmacytoma accounts for about 3% of all malignant plasma cell diseases. It is a single, isolated plasma cell tumor that originates in the bones and is common in middle-aged and elderly people, with a higher prevalence in men than in women. Isolated plasma cell tumors often invade the vertebral skeleton, and the other preferred sites are the pelvis, femur, humerus, and ribs in order of prevalence.
The main clinical features of isolated plasmacytoma are localized bone mass, accompanied by pain, and osteolytic lesions on imaging, with sharp and unclear borders, mostly in the form of “porous” or “soap bubble”. Currently, local radiotherapy is the first choice for treatment, and if the lesion is limited and easy to remove, surgical resection followed by local radiotherapy is preferred.
It is recommended that patients with isolated plasmacytoma should seek timely medical treatment, standardize the diagnosis and treatment under the guidance of specialists, early detection and early treatment to avoid delaying the condition.