It has been clinically proven that the incidence of lumbar disc herniation is significantly higher in smokers than in nonsmokers. The main reason for this is that smoking increases respiratory disease and produces coughing symptoms, and coughing causes strong contraction of the abdominal and lumbar back muscles, which increases intra-abdominal pressure thereby increasing the internal pressure of the disc and predisposing to lumbar herniation. It has been shown that by injecting a certain dose of nicotine into the dog, a decrease in vertebral blood supply occurs. Although the cells within the intervertebral disc can only obtain nutrients from endplate infiltration, when the blood supply to the vertebral body is reduced, this can reduce the nutrients available to the disc by diffusion and affect its normal metabolism. It is generally accepted that there is a significant correlation between smoking and lumbar disc herniation, and that there is a dosage correspondence, i.e. the longer the smoking history and the more cigarettes smoked per day, the higher the chance of lumbar disc herniation.