Leakage is usually referred to as urinary incontinence. There are many causes of long-term urinary incontinence, such as stress incontinence, urge incontinence, and filling incontinence, etc. Commonly used therapeutic medications include Midodrine Hydrochloride, Tolterodine, Mirabephrine, and Tamsulosin, etc. Different types of incontinence are treated with different medications, and it is recommended that medications be used under the guidance of a doctor. Patients with stress incontinence can use alpha-agonists such as Midodrine Hydrochloride as prescribed by the doctor, but such drugs may have adverse reactions such as increased blood pressure, headache, sleep disorders, etc., and therefore should not be used for a long period of time. For those with urge incontinence, drugs such as tolterodine and mirabolone are commonly used. For those with urge incontinence caused by cystitis and other diseases, antibiotics such as levofloxacin and amoxicillin can also be used for treatment. For patients with filling incontinence, alpha-blockers such as tamsulosin and terazosin can be used, which can reduce the tension of the urethral smooth muscle, thus allowing the patient to empty the bladder. Patients with long-term urinary leakage, should promptly go to the hospital, by the doctor to clarify the cause of the disease, targeted treatment, not blindly self-medication. In addition, patients should pay attention to the care of the skin of the buttocks and perineum in daily life, keep dry to avoid the erosion of urine and damage to the skin.