Congenital heart disease is the most common type of congenital malformation, accounting for about 28% of all kinds of congenital malformations. It refers to the anatomical structure abnormalities caused by formation disorders or developmental abnormalities of the heart and large blood vessels during embryonic development, or the failure to close channels that should be closed automatically after birth (which is normal in the fetus). The incidence of congenital heart disease is not to be underestimated, accounting for 0.4% to 1% of births, which means that 150,000 to 200,000 new congenital heart disease patients are born each year in China. The spectrum of congenital heart disease is particularly broad, including hundreds of specific subtypes, some patients can be combined with a variety of malformations, the symptoms vary widely, the least can be asymptomatic for life, the most serious patients are born with serious symptoms such as hypoxia, shock and even premature death. According to the hemodynamic and pathophysiological changes, congenital heart disease can be classified as cyanotic or non-cyanotic, and can also be divided into three categories according to the presence or absence of shunts: no shunt (e.g. pulmonary stenosis, aortic constriction), left-to-right shunt (e.g. atrial septal defect, ventricular septal defect, patent ductus arteriosus) and right-to-left shunt (e.g. tetralogy of Fallot, large vessel dislocation). There are many types of congenital heart disease, and their clinical manifestations depend mainly on the size and complexity of the malformation. Complex and severe malformations can present with severe symptoms shortly after birth and can even be life-threatening. It should be noted that some simple malformations such as ventricular septal defect and patent ductus arteriosus can have no obvious symptoms in the early stage, but the disease can still potentially develop and worsen, and need timely diagnosis and treatment to avoid losing the opportunity of surgery. The main symptoms are: 1. frequent colds, recurrent respiratory infections, and susceptibility to pneumonia. 2. Poor growth and development, wasting, and excessive sweating. 3.Impotent sucking during breastfeeding, difficulty in feeding, or infant refusing to eat, choking and coughing, and shortness of breath in general. 4.Children complain of easy fatigue and poor physical strength. 5.Blue lips and nails or bruising after crying or activity, pestle-like fingers and toes. 6.Like squatting, fainting, hemoptysis. 7.Heart murmur is found on auscultation.