When cough and sputum appear in the advanced stage of lung cancer, expectorant drugs can be used first to relieve the cough, such as Ambroxol Hydrochloride Tablets or Phlegm Calming Tablets for phlegm treatment. If you cannot take them orally, you can also choose acetylcysteine solution for nebulized inhalation. In addition, it is important to clarify whether the cough and sputum are caused by a combination of bacterial infections. For example, if there is yellow or pus sputum, it is necessary to add antibiotics for treatment, and drugs such as cefuroxime tablets and cefoperazone preparations can be chosen. If the symptoms are severe, it is often necessary to give intravenous fluid treatment. In addition, it is also necessary to improve blood analysis, as well as lung CT and other related tests to clarify and find the specific cause.