Symptoms of advanced lung cancer may vary depending on the patient’s physique. The condition of advanced lung cancer is more serious and requires timely symptomatic treatment. As the tumor continues to grow and infiltrate, lung cancer may spread to distant sites and lead to dysfunction or failure of other organs. If the tumor invades the pleura, pericardium or vocal cords, it may cause pleural effusion, pericardial effusion or vocal cord paralysis; if liver or brain metastasis occurs in late stage of lung cancer, symptoms such as hepatomegaly, yellow marks, vomiting or coma may occur; if bone metastasis occurs in early stage, there is usually no symptom, but bone isotope scan may detect diseased bones; if right upper mediastinal lymph node metastasis occurs, it may cause head, face, neck or upper chest edema and jugular vein anger. Symptoms; lung cancer in advanced stage may present malignant mass, and the main clinical manifestations are extreme emaciation, weakness, neurasthenia, mental depression, etc. Hoarseness is an important manifestation of lung cancer. Hoarseness can occur after laryngitis, cold and acute bronchitis, thyroid surgery and pharyngeal surgery, as well as after improper vocalization, excessive speech or even heavy smoking and drinking. However, this type of hoarseness can usually be treated symptomatically or cured spontaneously with rest. Hoarseness caused by lung cancer, thyroid cancer and laryngeal cancer is completely different from the above type of hoarseness, especially lung cancer. Hoarseness caused by lung cancer often occurs suddenly, progresses rapidly, or even loses its voice completely, and most patients are accompanied by chest pain, etc., which has no effect even after rest and anti-inflammatory symptomatic treatment for more than two weeks. When lung cancer occurs, when the tumor compresses or invades the recurrent laryngeal nerve, symptoms such as hoarseness will appear. Especially, the left laryngeal recurrent nerve starts from between the aortic arch and the left main bronchus and travels a longer distance in the chest cavity than the right laryngeal recurrent nerve. Therefore, the left recurrent laryngeal nerve is more susceptible to thoracic lesions than the right. Generally speaking, when the laryngeal nerve is invaded and hoarseness appears, lung cancer can be considered to have developed to an advanced stage. What are the symptoms of lung cancer? 1. Fever in lung cancer is mostly caused by inflammation due to obstruction and poor drainage of bronchial cavity caused by cancer. Early treatment with antibiotics can restore the body temperature to normal, but it is prone to recurrence, and male smokers over 45 years old with long-term inflammatory fever in the lungs and poor treatment should be especially alert to the possibility of lung cancer. 2. Chest tightness and shortness of breath can be caused by tumor obstruction of bronchus and pulmonary inflammation, but it is usually more obvious in the late stage of lung cancer, especially when there is a lot of pleural fluid. 3. Chest pain is generally intermittent and not severe pain in the chest. It is dull pain or drilling pain, which can last for several minutes to several hours. If the cancer invades the pleura, the pain will be more intense, continuous and fixed. 4.Cough is the most common symptom, about 2/3 of patients have this symptom. It can be a mild dry cough or a severe cough with varying amount of sputum. However, in patients with chronic long-term cough once the nature of cough changes, or frequency or nocturnal cough appears, be alert to lung cancer. 5.Shortness of breath: if lung cancer cells metastasize a lot and cause fluid in the chest, patients will have symptoms such as chest tightness and wheezing, and some patients will have edema. 6.Cancer pain: shoulder pain is the most common.