, suggesting that the following drugs have evidence-based medical evidence and can be used for anti-tic disorder treatment: Perphenazine, Haloperidol, Fluphenazine, Methotrexate, Risperidone, Aripiprazole, Olanzapine, Quetiapine, Ziprasidone, Colistin, Guanfacine, Toltea, Baclofen, Botulinum toxin, Butenazol, Cannabinoids, etc. In 2013, the Pediatric Neurology Group of the Pediatric Branch of the Chinese Medical Association published “Recommendations for the Diagnosis and Treatment of Tic Disorders in Children” in the Chinese Journal of Pediatrics, suggesting that the first-line drugs for the treatment of tic disorders in children: thiopride, permethrin, sulpiride, aripiprazole, colistin, guanfacine; second-line drugs: haloperidol, risperidone, olanzapine, topiramate, sodium valproate.