The swelling and pain in the big toe for no apparent reason is as follows: a. Consider that the patient may have gouty arthritis. Gouty arthritis onset will have this kind of performance, obviously sleep better at night, in the middle of the night suddenly appeared red, swollen, hot, painful toes. This kind of red color dark red, purplish red, touch a hot, hot hands, swelling occurs especially quickly, just now is quite good, but soon swollen very large. The pain is so intense that a gust of wind can cause severe pain, even if the patient does not dare to go down to the ground or move his toes, and when the quilt is pressed on his toes, severe pain can be produced. So when such unexplained pain occurs, go to the hospital early to check the blood uric acid. If the blood uric acid is elevated, greater than 416 μmol/L, it can be identified as an acute attack of gouty arthritis. Second, bunions, aseptic inflammation of the bursa on the inside of the metatarsophalangeal joint of the thumb, may also produce swelling and pain.