The taste sensation in the anterior 2/3 of the tongue is mainly due to the innervation of the facial nerve, and the taste sensation in the posterior 1/3 of the tongue is innervated by the glossopharyngeal nerve. When loss of taste sensation occurs, the patient can be given sweet or saltier foods to determine the site of taste loss. Loss of taste is mainly due to nerve damage, with viral infections being the most common cause. Treatment requires oral antiviral and nerve-nourishing drugs, and if the patient does not have underlying diseases such as hypertension or heart disease, hormone shock therapy can be given as appropriate. In addition, intracranial CT or MRI should be completed to rule out acute cerebral infarction, cerebral thrombosis, or tumor compression. If the patient has any of these conditions, he or she should be given targeted treatment, such as thrombolysis, anticoagulation or surgery.