Levocanidin can usually improve sperm quality in about 3 months, but the onset of effect is not quite the same depending on each person’s different conditions and physique. Levocanidin is a commonly used medication in clinical practice, which is mainly used to treat and improve weak spermatozoa, and thus improve sperm vitality. Generally speaking, after using a course of treatment for at least 3 months, a review will be conducted to check the improvement of sperm quality. The spermatogenic cycle of spermatozoa is usually 72 days, that is, it takes 72 days for spermatogonia to develop into mature spermatozoa, therefore, 1 course of Zocanidin use, that is, the adjustment time for sperm quality, is usually set at 3 months. The usefulness of such drugs can only be determined after 1 to 2 courses of drug use, based on the improvement of sperm quality. For patients with poor sperm quality, it is recommended to visit the hospital in time and use the drug under the doctor’s guidance.