The increase in the cup-to-disc ratio in the early stages of the onset of hormonal glaucoma is irreversible. Hormonal glaucoma is a kind of secondary glaucoma caused by long-term systemic use of hormonal drugs or hormonal drops in the eye, etc., which leads to the proliferation of trabecular meshwork mesenchymal stromal cells inside the eye, causing an increase in the resistance to aqueous drainage and an increase in intraocular pressure. Hormonal glaucoma patients because of the elevated intraocular pressure, will compress the optic nerve, resulting in the thinning of the nerve fiber layer, it will cause the optic cup to optic disc ratio increases, and the optic nerve is non-renewable, once atrophy occurs can not be restored through treatment and so on, so the hormonal glaucoma, even if the cup-to-disc ratio expansion occurs in the early stage of the onset of the disease, it is irreversible. Hormonal glaucoma can be treated with eye drops to lower intraocular pressure, such as carteolol hydrochloride eye drops, or with surgery to lower intraocular pressure and prevent further aggravation of the condition. For hormonal glaucoma, it is recommended to consult a doctor in time for examination, clear diagnosis and early treatment.