The term “Er Xian Tang combined with Si Yi San plus and minus” refers to the use of the Chinese herbal formula Er Xian Tang together with Si Yi San at the same time, and the term “plus and minus” refers to the increase or decrease of medicines as appropriate according to the different conditions of the disease. The combination of Er Xian Tang and Si Reverse San has the effect of nourishing yin and tonifying yang, dredging the liver and regulating the spleen, and regulating Chong Ren. Er Xian Tang is effective in nourishing yin and tonifying yang, warming the kidneys and dispelling dampness, and regulating Chong Ren by the kidneys. It can treat kidney yang deficiency resulting in lumbar and knee soreness and tenderness, deafness and tinnitus, hot flushes (bursts of heat), night sweating (abnormal sweating after going to sleep, but sweating stops after waking up), etc. It is also effective in dispelling dampness by the kidneys. Si Reverse San has the efficacy of penetrating evil spirits to relieve depression, dredging the liver and regulating the spleen, and is mainly used for treating Yang depression and syncope syndrome (the main symptom manifests as lack of warmth in the hands and feet) and liver and spleen disorders. If you have the need for medication, it is recommended to go to the hospital and use the medication under the guidance of a doctor.