It takes about 5 years for the epiphyses to close, and the exact time of closure depends on the individual’s condition and gender, and cannot be generalized. During adolescent growth, there are epiphyses at the ends of the long bones and some of the flat bones. When the epiphyseal cartilage is completely ossified, the epiphyses close completely, and most females have their epiphyses close by the age of 18, and then close completely by the age of 23, while males have their epiphyses close by the age of 20, and then close completely by the age of 25. The epiphyseal closure depends not only on gender, but also on nutrition, exercise, genetics and other factors, so in adolescence, you should pay attention to balanced nutrition, adequate sleep and appropriate sports.