Signs of hepatic coma include liver damage, personality changes, and sleep abnormalities, which should be treated by a doctor in a timely manner. Patients with hepatic coma usually have liver injury and a significant decrease in liver function, resulting in their inability to degrade ammonia produced by the intestines, and a large amount of ammonia enters the blood circulation, leading to an increase in blood ammonia, which affects brain function, thus triggering coma. Patients are usually accompanied by symptoms of primary liver disease, such as ascites, jaundice, and loss of appetite. In addition, before the increase of blood ammonia reaches the level of hepatic coma, patients may have symptoms such as sleep disruption, personality change, anxiety, poor concentration, forgetfulness, and mental indifference, which suggests that the patient may have signs of hepatic coma, and should consult a doctor in a timely manner. When patients have the above symptoms, they should consult a doctor in time and follow the doctor’s instructions to carry out the corresponding treatment, avoiding blind judgment on their own, so as to avoid delaying the condition.