Lung lymphoepithelioma-like carcinoma can be treated with immunotherapy if the test is positive, but not if it is negative. Lung lymphoepithelioma-like carcinoma is a relatively rare type of non-small cell lung cancer, there is no way to determine whether immunotherapy is possible from its pathological type alone, and it needs to be analyzed in conjunction with the results of immunohistochemistry. If the result of the test is positive, it means that it meets the criteria for immunotherapy and can be treated with immunotherapy; however, if it is negative, it means that it is not suitable for immunotherapy. Immunotherapy for lung lymphoepithelioma-like carcinoma has relatively less side effects and more outstanding effect, but the cost is more expensive, so it is recommended to choose according to personal situation and doctor’s advice.