Taking lenalidomide skin allergy need to stop using the drug, for skin allergy treatment and adjust the medication. 1. Stop taking the drug: when skin allergy occurs after taking lenalidomide, you can consider temporarily stop taking oral lenalidomide, and observe whether the skin allergy symptoms are relieved after stopping taking lenalidomide. 2. Symptomatic treatment: When skin allergy, itching, redness and swelling are more serious after taking lenalidomide, you can consider oral loratadine and other allergy medicines to relieve the symptoms. 3. Adjustment of medication: Lenalidomide skin allergy is a common adverse drug reaction. If the allergic symptoms are relieved, patients can switch to other drugs under the guidance of a specialist. Oral lenalidomide skin allergy specific treatment methods, should be under the guidance of a specialist, it is recommended that patients go to the regular hospital in a timely manner.