Toothache during pregnancy may be caused by caries, acute wisdom teeth pericoronitis, gingivitis and other diseases, need to take general measures, medication for the cause. 1. Caries: common symptoms are black teeth, cavities, toothache and so on. Patients need to go to the hospital for filling and repairing the caries hole, commonly used materials are composite resin, glass ionization and so on. Caries has caused pulpitis also need to carry out root canal treatment. 2. Acute wisdom teeth pericoronitis: the main performance is tooth pain, facial swelling. Patients need to follow the medical advice to use saline, 0.1% chlorhexidine and other solutions to rinse the blind pocket. If you are in the middle or late stages of pregnancy, you can use metronidazole as prescribed by the doctor, but it is forbidden to use the drug in the first trimester of pregnancy. 3. Gingivitis: patients will have toothache, bleeding gums and other symptoms. For pregnant women with severe inflammation, antibacterial solutions with low irritation such as chlorhexidine gluconate gargle can be used under doctor’s guidance, and 1%~3% hydrogen peroxide solution should be used to rinse the gingival sulcus in conjunction with the doctor. When a pregnant woman has a toothache, she needs to go to the hospital in time, cooperate with the doctor to actively treat the primary disease and strengthen oral management.