Gammaglobulin infusion in children can improve the effectiveness of clinical antibiotics and the immunity of children, which is a passive immunization method, but we should also pay attention to its side effects, which are prone to allergic reactions. Some children produce antibodies to the IgA in gammaglobulin, and when gammaglobulin is injected, an allergic reaction occurs, causing generalized fever, chills, and rash, and these symptoms will disappear slowly over time. However, in a small number of patients, this symptom occurs after using gammaglobulin for many days, so it is important to keep an eye on the changes in the condition. In addition, since gammaglobulin contains a small amount of anti-A or anti-B lgG, it can affect blood circulation and cause hemolysis, which is a blood system symptom, so it is also necessary to pay attention to it.