Fever after vaccination can be treated with physical cooling, fever over 38.5 ℃ can be taken under the guidance of the physician oral antipyretic drugs, persistent high fever for more than 24 hours need to consult a doctor. Fever after vaccination belongs to the common adverse reaction of vaccine. If the body temperature is below 38.5℃, it belongs to the range of low fever, and you can carry out physical cooling treatment by yourself. Using a towel soaked in cold water and wiping it on the forehead or other parts of the body can effectively lower the body temperature. If after physical cooling, the body temperature continues to rise, appearing more than 38.5 ℃ high fever, then need to take oral antipyretic drugs under the guidance of a physician. If the fever persists for more than 24 hours, we should consult a doctor in time, under the guidance of the doctor to carry out blood tests to determine whether the bacterial infection, and at the same time, use acetaminophen and other antipyretic drugs to control the body temperature, to avoid other adverse consequences caused by fever. Therefore, low fever can be physical cooling, body temperature over 38.5 ℃ oral antipyretic medication, if the high fever lasts more than 24 hours, then we need to consult a doctor in a timely manner, after a clear diagnosis for targeted treatment.