Multiple gallbladder polyps are better than solitary gallbladder polyps because the cancer rate of solitary gallbladder polyps is higher, while most of the multiple gallbladder polyps are benign. Cholesterol polyps belong to multiple gallbladder polyps, and there are also surgical problems that meet the following conditions that require surgery: 1, multiple polyps with those larger than 1 cm must be operated; 2, polyps with symptoms, such as right upper abdominal discomfort, accompanied by gastrointestinal symptoms should also be operated; 3, multiple polyps are often accompanied by stones and gallstones, which should also be surgically treated. In conclusion, multiple polyps of the gallbladder are mainly benign lesions and have a better prognosis than solitary polyps. Generally, multiple gallbladder polyps are more benign than solitary gallbladder polyps, but they cannot be taken lightly because some of them must be treated surgically, such as larger polyps, polyps with gallbladder stones or gradually growing polyps, and polyps over 1cm, which must be alert to the occurrence of gallbladder cancer and need surgical treatment. Gallbladder cancer is a disease with a high degree of malignancy in clinical practice, so it must be taken seriously.