Staying up late can lead to an increase in blood pressure. When staying up late, patients will experience dysfunction of the nervous, humoral, and endocrine systems, thus leading to an imbalance in systolic and diastolic blood pressure, which can lead to an increase in blood pressure. Staying up late will cause the patient to be sympathetically overexcited, and secondary hypertension will occur at this time. In addition, if the patient has a high salt and high fat diet when staying up late, it will further aggravate the water and sodium retention, so there will be a continuous increase in blood pressure. Patients with increased blood pressure caused by staying up late should try to go to bed early, get up early, avoid staying up late and overworking, have a low-salt, low-fat, low-sugar diet, quit smoking and drinking, and should do aerobic exercise appropriately and adjust the quality of sleep to be able to restore blood pressure to normal.