There are many reasons why you want to cough when you take a deep breath, and the common ones are pharyngitis, bronchial asthma, tuberculosis, and pleural diseases. 1. Pharyngitis: it is possible that the mucous membrane of the throat wall is stimulated when breathing to cause coughing. 2. Bronchial asthma: Most of them have a history of allergy, increased airway reactivity, and coughing when taking a deep breath. Its clinical manifestations are recurrent wheezing, shortness of breath, chest tightness or cough and other symptoms, night and early morning attacks or aggravation is an important clinical feature of asthma, most patients can be relieved on their own or after treatment. 3. Tuberculosis: If coughing when taking a deep breath is accompanied by low-grade fever, night sweats, decreased body resistance and emaciation, it may be related to tuberculosis. 4. Pleural disease: for example, pleurisy, deep breathing will have a coughing reaction. There are other reasons for coughing when you take a deep breath, so we suggest that you go to the hospital in time and have a further examination to clarify the cause of the disease as soon as possible, and carry out treatment under the guidance of the doctor.