Blood pressure systolic pressure is always around 150 mmHg that cannot be lowered, at this time the patient should be advised to adjust the type of antihypertensive drugs taken or start a combination drug regimen to further lower the blood pressure. Patients who are currently taking types of antihypertensive drugs such as Irbesartan and Telmisartan are advised to add Hydrochlorothiazide tablets, which will help lower blood pressure relatively better. If the patient is currently taking a calcium channel blocker like amlodipine, felodipine, it is recommended that the patient combine it with a sartan drug, or add a beta-blocker. The representative drugs of beta-blockers are bisoprolol, metoprolol, etc. While adjusting the medication regimen, attention should be paid to combining it with lifestyle interventions to improve it, which will help to better reduce the patient’s This will help to reduce blood pressure.