If the patient has chest tightness and panic at night, the following points should be considered: first, consider the endocrine metabolic diseases, when the patient has severe thyroid dysfunction, parathyroid dysfunction and adrenocortical dysfunction, the patient will have an increase in vagal tone, and therefore, there will be a series of clinical symptoms and reactions such as chest tightness, shortness of breath, panic, palpitations, and precordial discomfort, especially in the evening and at night. Secondly, if the patient has the above situation, the patient will have a series of clinical symptoms and reactions. Secondly, if the patient has the above situation, the patient should also consider the vegetative nerve dysfunction, especially in the cardiac neurosis patient, in the night, especially easy to lead to chest tightness, shortness of breath, heart panic clinical symptoms. Third, if the patient appears, for example, women in puberty and menopause before and after the body’s estrogen and progesterone secretion imbalance, will also have this symptom. Fourth, for organic heart disease, often in the case of coronary heart disease unstable angina, or acute myocarditis, etc., triggering arrhythmia, resulting in chest tightness and panic at night.