Diarrhea and gastroenteritis, acute bacillary dysentery, intestinal tuberculosis, etc., and patients taking antidiarrheal drugs ineffective may be insufficient with the amount of medication, a single drug, etc., can follow the doctor’s instructions for drug treatment. 1. Gastroenteritis: some gastroenteritis patients with insufficient medication, a single drug, there may be taking antidiarrheal drugs ineffective phenomenon. Usually patients need to follow the doctor’s instructions for the joint application of azithromycin, amoxicillin and other antibacterial drugs, but also follow the doctor’s instructions to adjust the dosage of antidiarrheal drugs to alleviate the symptoms of diarrhea. 2. Acute bacillary dysentery: for clear diarrhea caused by disease, taking antidiarrheal drugs is ineffective, in addition to complying with the doctor’s instructions to adjust the dosage, but also need to comply with the doctor’s instructions to use ciprofloxacin, ceftriaxone sodium and other antibiotics. If the patient is accompanied by severe abdominal pain, belladonna tablets or atropine can be used to relieve. 3. Intestinal tuberculosis: patients with intestinal tuberculosis generally need to take anti-tuberculosis treatment, and the simple use of antidiarrheal drugs can not relieve diarrhea symptoms. Commonly used anti-tuberculosis drugs are isoniazid, rifampicin, pyrazinamide, ethambutol, streptomycin and so on. It is recommended to take antidiarrheal drugs for diarrhea ineffective people timely medical examination, clear disease, follow the doctor’s instructions for medication. It is worth noting that people who do not have a clear cause of diarrhea should not use drugs on their own, so as not to cover up or aggravate the condition.