Taking atorvastatin may cause muscle weakness, but not the disease myasthenia gravis. Atorvastatin is a common statin lipid-lowering drug, which can be used to treat hypercholesterolemia, for the prevention and treatment of cardiac atherosclerosis, cerebrovascular and peripheral vascular atherosclerosis, and so on. Long-term use may cause rhabdomyolysis, leading to muscle pain, weakness and other symptoms. Common adverse reactions to atorvastatin are manifested in the impairment of liver function, which may be characterized by jaundice, deepening of urine color, abdominal discomfort, loss of appetite, which may be accompanied by elevation of glutamic oxaloacetic transaminase and glutamic alanine aminotransaminase. Adverse reactions in the musculoskeletal system are often characterized by muscle weakness, dull ache, skeletal muscle pain, muscle cramps, sometimes accompanied by elevated creatine kinase. Patients should pay attention to standard low cholesterol dietary control when using atorvastatin, allergy to the product or active liver disease is prohibited, use should be detailed consultation with a doctor, under the guidance of the doctor reasonable use of drugs.