Coma in cerebral infarction is a disorder of consciousness due to cerebral infarction and is mainly seen in patients with large hemispheric infarction and brainstem infarction. Impaired consciousness includes drowsiness, somnolence and coma, and coma is divided into shallow coma, moderate coma and severe coma. Severe coma is the most severe type of disorder of consciousness and generally has a high mortality rate. If patients occasionally survive, they usually have some sequelae and their disability rate is high, which seriously affects the quality of life. Patients usually have cerebral edema and increased intracranial pressure, and if coma occurs, they should be given brain-awakening treatment in time. Commonly used drugs include brain-awakening sedative, compound musk injection and Qingkailing injection. If the intracranial pressure is increased, the patient should also be given cranial pressure lowering treatment, and the commonly used drugs include mannitol, glycerol fructose and tachyphylaxis, etc.