Parathyroid hyperplasia does not necessarily require surgery. Parathyroid hyperplasia may cause excessive secretion of parathyroid hormone or high blood calcium, leading to hyperparathyroidism, and may even induce hypercalcemia, which involves multiple systems of the body and may require surgery. However, when hyperparathyroidism is caused, there is no significant elevation of blood calcium, and it is not accompanied by other symptoms, so it does not have surgical indications and does not necessarily require surgery. If parathyroid hyperplasia patients have significantly elevated blood calcium, accompanied by other symptoms or complications, and have a history of hypercalcemia in the past, surgery must be performed in order to cure the disease. Therefore, whether parathyroid hyperplasia should be operated or not mainly depends on the parathyroid hormone level, blood calcium and other indexes, and combined with the professional doctor’s therapeutic advice, standardized treatment and medication under the guidance of the professional doctor, so as to avoid delaying the condition.