Genital herpes causing vulvar skin cracks can be oral antiviral drugs such as acyclovir, famciclovir; also can be used externally, such as acyclovir cream, famciclovir ointment, phosphonate cream and so on. The principle of treatment is based on antiviral and infection prevention. 1. Acyclovir: it is an antiviral drug, mainly used for herpes simplex virus infection, and can also be used for herpes zoster. 2. Famciclovir: Famciclovir is also an antiviral drug, mainly used for infections caused by herpes virus, such as genital herpes and shingles. 3. Acyclovir cream: Acyclovir cream is an antiviral topical preparation mainly used for some viral infections of the skin, such as herpes simplex and shingles. 4. Famciclovir Ointment: Famciclovir cream is an antiviral medicine, mainly used for treating some diseases caused by herpes simplex virus infection, with anti-inflammatory and antiviral effects. 5. Sodium phosphonate cream: Sodium phosphonate cream is a kind of topical medicine that inhibits reverse transcriptase and is used in patients with impaired immune function or acyclovir-resistant herpes simplex viral skin and mucous membrane infections. If genital herpes causes cracks in the vulvar skin, it is recommended to go to the hospital in time for early and regular treatment, and all the above medications should be used under the guidance of a doctor.