Reflux esophagitis is a group of diseases in which stomach contents (including stomach acid and bile) reflux into the esophagus, resulting in clinical symptoms or complications such as inflammation, ulceration, and stricture, and is classified as gastroesophageal reflux disease (GERD). GERD is characterized clinically by a burning sensation or pain behind the sternum, gastroesophageal reflux, dysphagia, bleeding and anemia, and complications such as esophageal stricture. The severity of esophagitis does not correlate with reflux symptoms. Patients with reflux esophagitis may have typical symptoms of GERD, but may also have no symptoms of reflux and may present with indigestion such as epigastric pain and discomfort. The clinical presentation of patients with severe esophagitis is not necessarily severe. Typical symptoms manifest as burning sensation behind the sternum (heartburn), reflux and chest pain. Heartburn is a burning sensation behind the sternum radiating to the neck, and reflux refers to the reflux of stomach contents into the pharynx or mouth. Reflux symptoms tend to occur after a full meal and affect the patient’s sleep at night when reflux is severe. Later in the disease, esophageal scar formation narrows and the burning sensation and burning pain gradually decreases, but permanent difficulty in swallowing occurs and can cause blockage or pain when eating solid food. In severe esophagitis, bleeding may occur due to esophageal mucosal erosion, mostly chronic and small. Long-term or heavy bleeding can lead to iron deficiency anemia.