Female patients with lumbar pain when lying down, the common causes are mainly the following: 1, lumbar spine tuberculosis, mostly seen in female patients with previous pulmonary tuberculosis, tuberculosis bacilli spread to the lumbar spine through the blood, can cause local pain, swelling, pain symptoms can be significantly increased when the patient lying down. In this case, the patient can improve the lumbar spine magnetic resonance imaging or CT examination to clarify the specific location of the lesion, as soon as possible to carry out anti-tuberculosis treatment to clear the body of Mycobacterium tuberculosis, and if necessary, feasible surgery to remove the local lesion to play a complete cure. 2, the patient’s lumbar spine with subcutaneous cysts and infection, can form a large volume of inflammatory mass, lying down when the mass is compressed and cause obvious pain symptoms. Patients are treated by local disinfection and antibiotics to promote local inflammation absorption. For patients with abscess formation, abscess incision and drainage are needed to strengthen anti-infection treatment, which can relieve the symptoms of lumbar pain more quickly.