After the application of delay spray or second ejaculation (premature ejaculation), may be related to the application of improper, psychological factors and the impact of other organic factors. 1. Improper application: most of the main components of the delay spray for local anesthetic drugs, should be applied about half an hour before intercourse. If sprayed earlier or sprayed immediately after intercourse, will affect the effect of the drug play, the phenomenon of premature ejaculation. 2. Psychological factors: delay spray is mainly through the anesthesia of the glans and the coronary groove to reduce sensitivity, and then play the role of delay. For anxiety, lack of self-confidence, mental stress and other psychological factors caused by premature ejaculation, it is difficult to have a good effect, and then after the use of drugs, will continue to appear premature ejaculation phenomenon. 3. Other organic factors: In addition to high glans sensitivity and the above psychological factors, premature ejaculation may also be related to brain neurotransmitter abnormalities, hormone level abnormalities, etc., the application of time-lapse sprays, the same may not be able to play a better efficacy, and then continue to appear premature ejaculation phenomenon. It is recommended that patients seek medical examination and treatment according to the results of the examination. If you need to apply delay spray, the corresponding medication and contraindications, should also follow the guidance of the doctor.