Clinically used drugs to dissolve gout stones are divided into two categories, drugs that inhibit uric acid production and drugs that promote uric acid excretion. 1. Inhibit the generation of uric acid: commonly used allopurinol, febuxostat, etc., can inhibit xanthine oxidase, so as to block xanthine and this xanthine to the conversion of uric acid, reduce the level of uric acid in the serum. 2. Promote uric acid excretion of drugs: commonly used benzbromarone, probenecid, etc., the mechanism of inhibition of renal tubular reabsorption of uric acid to increase uric acid excretion, but the existence of uric acid stones is prohibited. The above two drugs for the smaller size of the gout stone dissolution has a certain help, need to be under the guidance of the doctor reasonable use of drugs. For larger size gout stones, surgical treatment such as gout stone removal should be used under doctor’s advice. Patients with gout stones are advised to go to the rheumatology and immunology departments of regular hospitals for detailed consultation and treatment according to the doctor’s instructions.