Endocrine disorders may cause swelling of the face in the morning, usually seen in endocrine disorders related to thyroid hormones and cortisol hormones. It can also be seen in other diseases, it is recommended to improve the relevant examination. Endocrine disorders refer to the disruption of hormones secreted by some glands of the endocrine system, which can lead to a series of clinical manifestations, such as insomnia, depression, facial swelling, acne, hair loss, obesity, and high blood pressure. Swelling of the face is mostly due to thyroid hormone, cortisol hormone abnormalities, but also can be seen in other diseases, it is recommended to improve the relevant examination. It is recommended that patients with swollen face in the morning go to the hospital in time, under the guidance of the doctor to clarify the cause of the disease, so as to carry out targeted treatment.