Once diagnosed, hyperkalemia caused by renal disease should be treated aggressively, firstly, all potassium-containing drugs or solutions should be discontinued immediately, and calcium gluconate should be given to protect the myocardium. In order to reduce the blood potassium concentration, drug treatment (such as furosemide, polysulfonated styrene exchange resin, etc.) can be adopted, and dialysis treatment is feasible if the drug efficacy is poor. Drug therapy: including furosemide diuretic potassium excretion; calcium gluconate to counteract the damage of potassium to myocardium; glucose + insulin to promote the transfer of potassium; 5% sodium bicarbonate solution intravenously, which can promote the transfer of potassium into the cells or by urinary excretion; oral polysulfonated styrene-exchange resin for intestinal excretion of potassium and so on. Dialysis treatment: the most rapid and effective way to reduce blood potassium, there are two kinds of hemodialysis and peritoneal dialysis, the former can remove potassium faster than the latter, and it can be used for patients who can not reduce the concentration of blood potassium after the above treatments or patients with severe hyperkalemia. The above medication should be used in accordance with the doctor’s prescription, and should not be used without authorization. Hyperkalemia caused by nephropathy is a more serious and critical disease, and should go to the nephrology department or emergency department of regular hospitals for consultation and standardized treatment after evaluation by doctors.