For the drug treatment of black stool need to clarify the cause of targeted treatment, ordinary people due to dietary reasons, such as the consumption of spinach, black sesame, duck blood, etc., there will be black stool, reasonable adjustment of the diet can be relieved, some patients may be due to peptic ulcer, rupture of the esophagogastric fundal varices bleeding and other causes, commonly used drugs such as omeprazole enteric-coated tablets, growth inhibitors, and so on. 1. Physiological factors: due to dietary reasons, such as eating foods containing melanin (such as black beans, black sesame, etc.) or high iron content (such as spinach, duck blood, etc.) will appear black stools, usually after dietary adjustments, black stools will gradually disappear. 2. Peptic ulcer: such as gastric ulcer, duodenal ulcer, at present, commonly used drugs such as omeprazole enteric-coated tablets, rabeprazole and so on for acid-suppressing treatment. At the same time, the use of teprenone capsules or aluminum thioglycollate gel for mucosal protective treatment. Patients with definite Helicobacter pylori infection need eradication treatment. 3. Bleeding from rupture of esophagogastric fundal varices: the aim of treatment is to control acute bleeding and prevent rebleeding. Treatment means include medication such as octreotide, growth inhibitor, etc., triple lumen tube balloon compression for hemostasis, endoscopic ligation treatment and surgical treatment. 4. Gastric cancer: gastric cancer can infiltrate the mucosa and blood vessels, causing damage and bleeding. Surgical resection is still the main treatment for early gastric cancer and the main means to treat gastric cancer. If you have black stools, please go to the hospital for diagnosis and treatment in time after eliminating physiological reasons, so as to avoid delaying your condition.