The main reason for the soreness and pain in the thighs after getting cold is that the cold stimulation leads to vasoconstriction in the lower limbs, resulting in poor blood circulation in the lower limbs, leading to relative ischemia and hypoxia, and anaerobic metabolism in the tissues, leading to an increase in the accumulation of anaerobic metabolites, stimulating the local tissues to become sore and painful. First, remove the cause of the disease, do not let the lower limbs in the feeling of cold stimulation, pay attention to the warmth of the limbs. Secondly, it is better to brake the limbs to rest and reduce the amount of activity and exercise to prevent the anaerobic metabolism from continuing to increase, thus producing an aggravation of the symptoms. Third, local physical therapy, hot compresses, massage, spectrum irradiation, moxibustion and other treatments can be carried out to restore local blood circulation. If the symptoms are obvious, you can apply topical medication to promote blood circulation, reduce swelling and pain, and also take oral anti-inflammatory and analgesic anti-inflammatory drugs, such as fenbendazole and celecoxib. Generally, the soreness of the lower limbs caused by cold will be relieved soon after the above treatment of warmth, rest and support of allopathic and physical therapy.