Toothache eat cephalosporin generally does not make the tooth more painful, in fact, endodontitis eat cephalosporin, does not have a certain role, not all toothache can eat cephalosporin. 1. Cephalosporin is an anti-broad-spectrum antibiotic, which can be distributed in various parts of the body after use, and effectively fights against a variety of antibiotic infections. It can be used as an adjunctive medicine for toothache. 2. There are many reasons for tooth pain, including pulpitis, periodontitis, periapical inflammation, pericoronitis and other causes. Pulpitis inflammation is confined to the root canal, pulp cells liquefy and decompose, generating pressure and severe pain, the use of antibiotics such as cephalosporin is not useful, you need to go to the root canal in time, but it will not aggravate the symptoms of pain. 2. apical periodontitis, pericoronitis, inflammation in the apical region or periodontal localized inflammation using cephalosporin is useful, can only be used as an adjunctive treatment, but also need to go to the stomatology department for the corresponding cause of the corresponding treatment. Toothache needs timely medical treatment, avoid self-medication, in order to avoid adverse effects.