Itchy skin during sleep may be related to poor bathing practices, pruritus, exposure to allergens and other factors. 1. Bad bathing: patients may have the habit of taking a hot bath before going to bed, excessive scalding of hot water, excessive cleaning of the skin, the use of alkaline toiletries, etc., will remove the oils on the surface of the skin, which will cause skin dryness, and itchy skin symptoms when sleeping. 2. Pruritus: itchy skin when sleeping, not exclude is due to pruritus, such as in lying down to sleep, may be due to chemical fiber clothing stimulation, bedding is too hot, live and work in poor environmental hygiene conditions and so on, so there will be itchy skin symptoms. 3. Contact with allergens: itchy skin while sleeping, do not rule out and patients contact allergen factors, such as indoor pollen, fungal spores, dust mites, animal dander, etc., the patient’s body is more sensitive to skin contact with allergens and produce skin itching. Sleeping itchy skin is likely to have other reasons, the patient can go to the hospital, by a professional physician to diagnose, and then do targeted treatment and therapy.