The severity of blinking and mouth corner twitching needs to be based on the patient’s specific situation. If it is caused by fatigue, it can usually recover on its own; if it is caused by craniocerebral related diseases, it will be more difficult to recover. 1. Functional lesions: If you look at the cell phone for a long time, excessive facial exertion, prolonged mental tension and stress, it may lead to transient facial muscle spasm, and the symptoms of blinking and twitching at the corners of the mouth will appear. Symptoms can be relieved by hot compresses and rest, and usually no special treatment is needed. 2. Intracranial organic lesions: such as cerebrovascular disease, demyelinating lesions, etc., blinking and twitching of the corners of the mouth may occur when the facial nerve is compressed or damaged. It can be treated with drugs for secondary prevention of cerebral infarction (e.g. aspirin, etc.), nutritive nerve drugs (e.g. methylcobalamin, etc.), or even hormone and other related drugs as prescribed by the doctor, but the recovery is usually poor. There may be other reasons for blinking eyes and twitching at the corner of the mouth, which require further hospitalization in the Neurology Department of the hospital in time.