Serum PSA739 is usually serious, serum PSA full name is prostate-specific antigen, serum prostate-specific antigen normal value does not exceed 4 ng/mL, if the serum prostate-specific antigen significantly increased, should be highly suspected of prostate cancer. Serum prostate-specific antigen is secreted by the epithelial cells of prostate follicles and ducts and is specific to prostate tissue. Serum prostate-specific antigen is the current biological indicator for prostate cancer, and its elevation suggests a higher possibility of prostate cancer. However, there are many factors affecting the prostate-specific antigen, such as prostate hyperplasia, prostatitis, age, transrectal fingerprinting, prostate massage and puncture, cystoscopy, and prostate surgery, which can cause the serum prostate-specific antigen to be elevated to different degrees. The normal value of serum prostate-specific antigen is not more than 4 ng/mL. If the value of prostate-specific antigen is 739 ng/mL, prostate cancer should be highly suspected, and immediate medical attention is needed to review the serum prostate-specific antigen and perform a prostate puncture biopsy to clarify whether it is prostate cancer. If the serum prostate-specific antigen is found to be elevated, further examination should be conducted under the guidance of a doctor to clarify the cause of the disease and early diagnosis and treatment.